Students will gain a foundation level understanding of the biochemical, cellular and tissue responses that can arise as a consequence of injury to cells, tissues and body organ systems. This understanding will be developed in the context of the aetiology and pathogenesis of the basic pathological processes including the degenerations, inflammation and sequelae, immunological reactivity, hypertrophy and hyperplasia, healing and neoplasia. This subject will also provide students with detailed knowledge and diagnostic capability in relation to specific pathology associated with teeth in their embryonic and posteruptive environments. # Introduction, definitions and contexts in general and oral health # Injury and human disease expression # Genetics and human disease # Cell and organ degenerations # The immune system functions & review of homeostatic mechanisms # The hypersensitivities and autoimmune disease # Acute inflammation and sequelae # Chronic inflammation & granulomatous inflammation and sequelae # The inflammatory process and immune system interactions # Healing and regeneration of soft tissues and bone # Complications of healing # Hypertrophy and hyperplasia # Neoplasia # Developmental abnormalities of teeth and the dental tissues # Dental caries # Inflammatory periodontal disease # Injury to the pulp-dentine complex # Tooth resorption # Odontogenic cysts # Introduction to the odontogenic tumours